AN UNBIASED VIEW OF NAD+ FOR IMPROVED IMMUNE SYSTEM FUNCTION

Next, we dealt with cells with distinct concentrations of NAD+. When additional for twenty-four h at eighty µM in HeLa and four hundred µM in U2OS cells, NAD+ impaired the incorporation of EdU (Fig. 2a and Extended Info Fig. 1k,l). Additionally, sixteen µM of NAD+ was sufficient to scale back fork velocity by ~forty% in HeLa cells withou